ACIN1 anticorps (AA 994-1009)

N° du produit ABIN1886906

L’anticorps Lapin Polyclonal anti-ACIN1 a été validé pour WB et ELISA. Il convient pour détecter ACIN1 dans des échantillons de Humain.

Aperçu rapide pour ACIN1 anticorps (AA 994-1009) (ABIN1886906)

Antigène: ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ACIN1 est non-conjugé

Application: Western Blotting (WB), ELISA

Détail du produit anti-ACIN1 anticorps

Épitope: AA 994-1009

Purification: Affinity chromatography purified via peptide column

Immunogène: Peptide corresponding to amino acids 994 to 1009 of human AcinusL, 267 to 282 of human AcinusS

Information d'application

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS containing 0.02 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.

Conseil sur la manipulation: Avoid freezing and thawing repeatly.

Stock: 4 °C/-20 °C

Stockage commentaire: Store at 4 °C for short term use.Store at -20 °C for long term preservation.

Détails sur ACIN1

Antigène: ACIN1 (Apoptotic Chromatin Condensation Inducer 1 (ACIN1))

Autre désignation: Acinus

Sujet: Chromatin condensation and nuclear fragmentation (CCNF) is the hallmark of apoptosis.CCNF is triggered by the activation of members of caspase family, caspase activated DNase (CAD/DFF40), and several novel proteins including AIF and CIDE.A new inducer of chromatin condensation was recently identified and designated Acinus (for apoptotic chromatin condensation inducer in the nucleus).Acinus is cleaved by caspase-3 and an additional unknown protease generating a small active peptide p17, which causes chromatin condensation in vitro when it is added to purified nuclei.Acinus also induces apoptotic chromatin condensation in cells.Acinus is ubiquitously expressed.Three different spliced forms of Acinus have been identified in human and mouse and designated AcinusL, AcinusS and AcinusS'.

Poids moléculaire: 220 kDa